Epac-mediated Activation of Phospholipase C Plays a Critical Role in -Adrenergic Receptor-dependent Enhancement of Ca Mobilization in Cardiac Myocytes*

نویسندگان

  • Emily A. Oestreich
  • Huan Wang
  • Sundeep Malik
  • Katherine A. Kaproth-Joslin
  • Grant G. Kelley
  • Robert T. Dirksen
  • Alan V. Smrcka
چکیده

Emily A. Oestreich, Huan Wang, Sundeep Malik, Katherine A. Kaproth-Joslin, Burns C. Blaxall , Grant G. Kelley**, Robert T. Dirksen, and Alan V. Smrcka From the Departments of Pharmacology and Physiology and the Cardiovascular Research Institute, University of Rochester School of Medicine, Rochester, New York 14642, Systems Biology Division, The Wistar Institute, Philadelphia, Pennsylvania, 19104, and Departments of Pharmacology and **Medicine, SUNY Upstate Medical University, Syracuse, New York 13210

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تاریخ انتشار 2007